Pathak, A.K., Pathak, V., Riordan, J.R., Suling, W.J., Gurcha, S.S., Besra, G.S., Reynolds, R.C. 2007. Synthesis of symmetrical C- and pseudo-symmetrical O-linked disaccharide analogs for arabinosyltransferase inhibitory activity in Mycobacterium tuberculosis. Bioorg. Med. Chem. Lett. 17:4527-4530.
Reynolds, R.C., Campbell, S.R., Fairchild, R.G., Kisliuk, R.L., Micca, P.L., Queener, S.F., Riordan, J.M., Sedwick, W.D., Waud, W.R., Leung, A.K.W., Dixon, R.W.,Suling, W.J., Borhani, D.W 2007. Novel boron containing, nonclassical antifolates:synthesis and preliminary biological and structural evaluation. J. Med. Chem. 50:3283-3289
Barrow, E.W., Suling, W. J., Seitz, L.E., Reynolds, R.C., Barrow, W.W. 2006. New antifolate inhibitors for Mycobacterium avium. Med. Chem. 2:505-510.
Xu, Z.Q., Pupek, K., Suling, W.J., Enache, L., Flavin, M.T. 2006. Pyranocoumarin, a novel ant-TB pharmacophore: Synthesis and biological evaluation against Mycobacterium tuberculosis. Bioorg. Med. Chem. 14:4610-4626.
Suling, W.J., Seitz, L.E., Reynolds, R.C., Barrow, W.W. 2005. New Mycobacterium avium antifolate shows synergistic effect when used in combination with dihydropteroate synthase inhibitors. Antimicrob. Agents Chemother. 49:4801-4803.
Reynolds, R.C., Srivastava, A., Ross, L.J., Suling, W.J., White, L.C. 2004. A new 2-carbamoyl pteridine that inhibits mycobacterial FtsZ. Bioorg. Med. Chem. Lett. 14:3161-3164.
Pathak, A.K., Pathak, V., Seitz, L.E., Suling, W.J., Reynolds, R.C. 2004. Antimycobacterial Agents. 1. Thio Analogues of Purine. J. Med. Chem. 47:273-276.
Xu, Z-Q., Barrow, W.W., Suling, W.J., Westbrook, L., Barrow, E., Lin, Y-M., Flavin, M.T. 2004. Anti-HIV natural product (+)-calanolide A is active against both drug-susceptible and drug-resistant strains of Mycobacterium tuberculosis. Bioorg. Med. Chem., 12:1199-1207.
Pathak, A.K., Pathak, V., Kulshrestha, M., Kinnaird, D., Suling, W.J., Gurcha, S.S., Besra, G.S., Reynolds, R.C. 2003. Arabinofuranose disaccharide analogs as inhibitors of Mycobacterium tuberculosis. Tetrahedron, 59:10239-10248.
Barrow, E.W., Westbrook, L., Bansal, N., Suling, W.J., Maddry, J.A., Parker, W.B., Barrow, W.W. 2003. Antimicrobial activity of 2-methyladenosine. J. Antimicrob. Chemother. 52:801-808.
Seitz, L.E., Suling, W.J., Reynolds, R.C. 2002. Synthesis and antimycobacterial activity of pyrazine and quinoxaline derivatives. J. Med. Chem. 45:5604-5606.
White, E.L., Suling, W.J., Ross, L.J., Seitz, L.E., Reynolds, R.C. (2002). 2-alkoxycarbonylaminopyridines: inhibitors of Mycobacterium tuberculosis FtsZ. J. Antimicrob. Chemother. 50:111-114.
Pathak, A.K, Pathak, V., Suling, W.J., Gurcha, S.S., Morehouse, C.B., Besra, G.S., Maddry, J.A., Reynolds, R.C. (2002). Studies on n-octyl-5-(β-D-arabinofuranosyl)-β-D-galactofuranosides for mycobacterial glycosyltransferase activity. Bioorg. Med. Chem. 10:923-928.
Rose, J.D., Maddry, J.A., Comber, R.N.,., Suling, W.J., Wilson, L.N., Reynolds, R.C. (2002). Synthesis and biological evaluation of trehalose analogs as potential inhibitors of mycobacterial cell wall biosynthesis. Carbohydrate Res. 337:105-120.
Chen, C-K., Barrow, E.W., Allan, P.W., Bansal, N., Maddry, J.A., Suling, W.J., Barrow, W.W., Parker, W.B. (2002). Biochemical and genetic characterization of the metabolism of 2-methyl-adenosine in Mycobacterium smegmatis. Microbiology, 148:289-295.
Pathak, A.K., Pathak. V., Maddry, J.A., Suling, W.J., Besra, G.S., Reynolds, R,C. (2001). Studies on α(1 5) linked octyl arabinofuranosyl disaccharides for mycobacterial arabinosyl transferase activity. Bioorg. Med. Chem. 9:3145-3151.
Pathak, A.K., Pathak, V., Seitz, L., Maddry, J.A., Gurcha, S.S., Flaherty, C., Besra, G.S., Suling, W.J., Reynolds, R.C. (2001). Studies on (β,1 5) and (β,1 6) linked octyl galf disaccharides as substrates for mycobacterial galactosyltransferase activity. Bioorg. Med. Chem. 9:3129-3143.
Suling, W.J. and Maddry, J.A. (2001). Antimycobacterial activity of 1-deaza-7,8-dihydropteridine derivatives against Mycobacterium tuberculosis and Mycobacterium avium complex. J. Antimicrob. Chemother. 47:451-454.
Suling, W.J.; Seitz, L.E.; Pathak, V.; Westbrook, L.; Barrow, E.W.; Zywno-van-Ginkel, S.; Reynolds, R.C.; Piper, J.R.; Barrow, W.W. (2000). Antimycobacterial activity of 2,4-diamino-5-deazapteridine derivatives and effects on mycobacterial dihydrofolate reductase. Antimicrob. Agents Chemother. 44:2784-2793.
Pathak, A.K.; Besra, G.S.; Maddry, J.A.; Morehouse, C.B.; Suling, W.J.; Reynolds, R.C. (1999). Studies on β-D-galf-(1 4)-α-L-rhap-octyl analogs as substrates for mycobacterial transferase activity. Bioorg. Med. Chem. 7:2407-2413.
Reynolds, R.C.; Bansal, N.; Rose, J.; Friedrich, J.; Suling, W.J.; Maddry, J.A. (1999). Etambutol-sugar hybrids as potential inhibitors of mycobacterial cell-wall biosynthesis. Carbohydrate Res. 317:164-179.
Suling, W.J.; Reynolds, R.C.; Barrow, E.W.; Wilson, L.N.; Piper, J.R.; Barrow, W.W. (1998). Susceptibilities of Mycobacterium tuberculosis and Mycobacterium avium complex to lipophilic deazapteridine derivatives, inhibitors of dihydrofolate reductase. J. Antimicrob. Chemother. 42(6):811-815.
Maddry,J.A.; Bansal, B.; Bermudez, L.E.; Comber, R.N.; Orme, I.M.; Suling, W.J.; Wilson, L.N.; Reynolds, R.C. (1998). Homologated aza analogs of arabinose as antimycobacterial agents. Bioorg. Med. Chem. Lett. 8:237-242.
Zywno-van Ginkel, S.; Dooley, T.P.; Suling, W.J.; Barrow, W.W. (1997). Identification and cloning of the Mycobacterium avium fol A gene, required for dihydrofolate reductase activity. FEMS Microbiol. Lett. 156:69-78.
Wright, E.L.; Quenelle, D.C.; Suling, W.J.; Barrow, W.W. (1996). Use of Mono Mac 6 human monocytic cell line and J774 murine macrophage cell line in parallel antimycobacterial drug studies. Antimicrob. Agents Chemother. 40:2206-2208.
Maddry, J.A.; Suling, W.J.; Reynolds, R.C. (1996). Glycosyltransferases as targets for inhibition of cell wall synthesis in M. tuberculosis and M. avium. Res. Microbiol. 147:106-112.
Struck, R.F.; Kirk, M.C.; Rice, L.S.; Suling, W.J. (1986). Isolation, synthesis and antitumor evaluation of spirohydantoin aziridine (SHAZ), a mutagenic metabolite of spirohydantoin mustard. J. Med. Chem. 29:1319-1321.
Suling, W.J.; Rice, L.S.; Shannon, W.M. (1983). Increased mutagenicity of chlorethylnitrosoureas in the presence of a rat liver S9 microsomal mixture. J. Natl. Cancer Inst. 70:767-769.
Struck, R.F.; Dykes, D.J.; Corbett, T.H.; Suling, W.J.; Trader, M.W. (1983). Isophosphoramide mustard, a non-urotoxic metabolite of ifosfamide with activity against murine tumors comparable to cyclophosphamide. Brit. J. Cancer 47:15-26.
Suling, W.J.; Struck, R.F.; Woolley, C.W.; Shannon, W.M. (1983). The metabolism of spirohydantoin mustard in the mouse: isolation of an alkylating, mutagenic metabolite. Biochem. Pharmacol. 32:523-527.
McCarthy, D.J.; Suling, W.J.; Hill, D.L. (1983). A comparison of the mutagenicity and macromolecular binding of the carcinogens Michler's ketone and reduced Michler's ketone. Mutation Res. 119:7-14.
McCarthy, D.J.; Struck, R.F.; Shih, T-W.; Suling, W.J.; Hill, D.L.; Enke, S.E. (1982). Disposition and metabolism of the carcinogen reduced Michler's ketone in rats. Cancer Res. 42:3475-3479.
Suling, W.J.; Woolley, C.W.; Shannon, W.M. (1979). Disposition and metabolism of bruceantin in the mouse. Cancer Chemother. Pharmacol. 3:171-176.
Suling, W.J.; Struck, R.F.; Woolley, C.W.; Shannon, W.M. (1978). Comparative disposition of phosphoramide mustard and other cyclophosphamide metabolites in the mouse using the Salmonella/mutagenesis assay. Cancer Treat. Rep. 62:1321-1328.
McConnell, W.R.; Suling, W.J.; Rice, L.S.; Shannon, W.M.; Hill, D.L. (1978). Use of microbiologic and enzymatic assays in studies on the disposition of 2'-deoxycoformycin in the mouse. Cancer Treat. Rep. 62:1153-1159.
Suling, W.J.; Rice, L.S.; Shannon, W.M. (1978). Effects of 2'-deoxycoformycin and erythro-0-(2-hydroxy-3-nonyl)adenine on plasma levels and urinary excretion of 9-β-D-arabinofuranosyladenine in the mouse. Cancer Treat. Rep. 62:369-373.
Suling, W.J.; O'Leary, W.M. (1977). Lipids of antibiotic-resistant and -susceptible members of the Enterobacteriaceae. Can. J. Microbiol. 23:1045-1051.
Suling, W.J.; O'Leary, W.M. (1975). The effect of surfactants on antibiotic resistance. Antimicrob. Agents Chemother. 8:334-343.
Albrecht, A.M.; Suling, W.J.; Hutchison, D.J. (1972). Metabolic control of the different forms of dihydrofolate reductase of the amethopterin-resistant Streptococcus faecium var. durans Ak. Arch. Biochem. Biophys. 153:16-25.
Albrecht, A.M.; Pearce, F.K.; Suling, W.J.; Hutchison, D.J. (1969). Folate reductase and specific dihydrofolate reductase of amethopterin-sensitive Streptococcus faecium var. durans. Biochemistry 8:960-967.
Parisi, J.T.; Suling, W.J. (1968). Antibiotic resistance of glycine-resistant variants of Staphylococcus aureus. Can. J. Microbiol. 14:811-812.