Life Sciences Research

High-Throughput Screening Program Publications


Peer-reviewed Papers

J.W. Noah, W. Severson, D.L. Noah, L. Rasmussen, E.L. White, and C.B. Jonsson. A Cell-based Luminescence Assay is Effective for High-throughput Screening of Potential Influenza Antivirals. Antiviral Research 73: 50-9, 2007

W. E. Severson, N. Shindo, M.I. Sosa, T.M. Fletcher III, E.L. White, S. Ananthan, and C.B. Jonsson. Development and Validation of a High Throughput Screen for Inhibitors of SARS CoV and its Application in Screening a 100,000 Compound Library. J. Biomol. Screen. 12: 33-40, 2007.

E.L. White, K. Southworth, L. Ross, S. Cooley, R.B. Gill, M.I. Sosa, A. Manouvakhova, L. Rasmussen, C. Goulding, D. Eisenberg, and T.M. Fletcher III. A Novel Inhibitor of Mycobacterium tuberculosis Pantothenate Synthetase. J. Biomol. Screen. 12: 100-105, 2007.

L. Rasmussen, C.B. Maddox, B. Harten, E. L. White. A Successful LIMS Implementation: Case Study at Southern Research Institute. J. Assoc. Lab. Automation. 12: 384-390, 2007.

C.B. Maddox, L. Rasmussen, E.L. White. Adapting Cell Based Assays to the High Throughput Screening Platform: Problems Encountered and Lessons Learned. J. Assoc. Lab. Automation 13:168-73, 2008.

W.E. Severson, M. McDowell, S. Ananthan, D.H. Chung, L. Rasmussen, M.I. Sosa, E.L. White, J. Noah, C.B. Jonsson. High-Throughput Screening of a 100,000 Compound Library for Inhibitors of Influenza A Virus (H3N2). J. Biomol. Screen. 13: 879-87,2008.

S. Ananthan, E. R. Faaleolea, R. C. Goldman, J. V. Hobrath, C. D. Kwong, B. E. Laughon, J. A. Maddry, A. Mehta, L. Rasmussen, R. C. Reynolds, J. A. Secrist III, N. Shindo, D. N. Showe, M. I. Sosa, W. J. Suling, E. L. White. High Throughput Screening for Inhibitors of Mycobacterium tuberculosis H37Rv. Tuberculosis 89:334-353, 2009.

J. A. Maddry, S. Ananthan, R. C. Goldman, J. V. Hobrath, C. D. Kwong, C. Maddox, L. Rasmussen, R. C. Reynolds, J. A. Secrist, M. I. Sosa, E. L. White, W. Zhang. Antituberculosis Activity of the Molecular Libraries Screening Center Network Library. Tuberculosis 89:354-363, 2009.

Book Chapters

D.L. Noah, E.L. White, and J.W. Noah. Development of High-Throughput Assays for Influenza, in Combating the Threat of Avian Influenza: Drug Discovery Approaches, Paul F. Torrence (ed), Willey and Sons (pub), Chapter2; p38-72 (2007).

Invited Reviews

C.B. Jonsson, E.L. White, W. Severson, and J. Noah. Going Hot - Creating a Roadmap for High Throughput Screening for Drug Discovery in Biosafety Level 3 Laboratories. Amer. Biotech. Lab. Accepted 2007.

C.B. Jonsson and E.L. White. Launching an HTS Campaign to Discover New Antivirals. Eur. Pharma. Rev. 3:36-39, 2007.

C.B. Jonsson, E.L. White, J. Noah, W. Severson, and M. Heil. The Search for Promising Viral Targets in Drug Discovery. Amer. Biotech. Lab. Vol. 25, August 2007.

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