Infectious Disease Research

Emerging Pathogens
Select Agents Program

Capabilities

• Bacterial
• Viral
• Toxins

Bacterial

• Bacillus anthracis (Anthrax)
• Francisella tularensis
• Other agents per request

Viral

• Current Capabilities
• Monkeypox virus
• Avian influenza virus (highly pathogenic)
• Other agents per requested
• In vitro program
• Anti-viral screening (LTS/HTS)
• Mechanisms of action studies
• Assay development
• In vivo program
• Vaccine/therapeutic efficacy testing (small/large animal models)
• Pathogenesis and model development
• Bioaerosol program
• In vitro services available:
• Hemagglutination-inhibition assays
• Neuraminidase-inhibition assays
• Reagent production
• Immunological assays (ELISA, Western blot)
• Custom assays
• Immune mechanisms
• Microneutralization assays
• Drug screening assays, including HTS
• GLP studies
• Consultation



• In vivo services available:
• Pathogenesis (small/large animal models)
• Vaccine safety/efficacy testing
• Production of hyper-immune sera
• Anti-viral testing
• Custom In vivo assays
• GLP studies
• Consultation
• Viruses:
• Current human influenza strains
• Mouse-adapted strains
• Highly pathogenic avian influenza viruses
• Novel or emerging influenza viruses

Toxins