Radiation

Southern Research has a Precision X-ray Inc., X-RAD 320 x-ray irradiator, fully calibrated, located in our in vivo laboratories where we conduct combination xenograft studies with human tumor models.

Our scientists have completed and published a radiosensitization study with clofarabine in the DLD-1 colon xenograft model. (View article.) And, we have evaluated the radiosensitizing potential of clofarabine in NCI-H460 lung, SR475HN head and neck, SF-295 glioblastoma, DU-145 prostate, PANC-1 pancreatic, and HCT-116 colon tumor models. (View AACR poster.)

In addition, we have established a radiation-induced mucositis model in rats. The x-ray irradiator is also available for in vitro survival assays using the clonogenic survival assay.

All of our xenograft models are available to clients for radiation studies. To speak with an experienced study director with a Ph.D. in radiation biology about any in vitro or in vivo radiation study, please contact us at: